Anti-Human/Mouse ZNF146 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]

ZNF146 (zinc finger protein 146), also known as OZF (only zinc finger protein), is a 292 amino acid nuclear protein that binds DNA and belongs to the Krüppel C2H2-type zinc-finger protein family. ZNF146 interacts with UBC9 (ubiquitin carrier protein 9) and RAP1 (repressor/activator protein 1 homolog), and is highly expressed in multiple pancreatic and colorectal cancers. Lower levels of expression have been observed in kidney, lung, placenta and brain.

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Properties

Data Sheet	Click for Datasheet
Catalog Number	PA02384
Size	100μl
Host Type	Rabbit
Immunogen	Synthetic peptide of human ZNF146
Specificity	Liver, skeletal and heart muscle, mammary cells. Very low levels in brain, lung, placenta and kidney. Strongly overexpressed in many pancreas and colorectal cancers. Increased gene copy numbers are detected in 3 of 12 tumor cell lines and 2 of 12 primary pancreatic carcinomas. Overexpresseed in 80% of colorectal cancers.
Isotype	IgG
Reacitivity	Human,Mouse
Clone
Uniprot	Q15072
Concentration	0.3 mg/mL
Dilution	IHC 1:25-100, ELISA 1:2000-5000
Formulation
Application	IHC,ELISA
Other Names	OZF
Storage	Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript	For research use only, not for use in diagnostic procedures.

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Anti-Human/Mouse ZNF146 Polyclonal Antibody

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