Anti-Human/Mouse VPS37A Polyclonal Antibody

This gene belongs to the VPS37 family, and encodes a component of the ESCRT-I (endosomal sorting complex required for transport I) protein complex, required for the sorting of ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies. Expression of this gene is downregulated in hepatocellular carcinoma, and mutations in this gene are associated with autosomal recessive spastic paraplegia-53. 
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Properties

Data Sheet Click for Datasheet
Catalog Number PA07418
Size 100μl
Host Type Rabbit
Immunogen Fusion protein of human VPS37A
Specificity Widely expressed. Examined tissues include heart, brain, placenta, liver, skeletal muscle, kidney and pancreas. More abundant in liver. Strongly decreased or undetected in hepatomas.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot Q8NEZ2
Concentration 0.8 mg/mL
Dilution WB 1:500-2000, IHC 1:25-100, ELISA 1:2000-5000
Formulation
Application WB,IHC,ELISA
Other Names 2210018P21Rik,4930592A21Rik,AW261445,D8Ertd531e,ESCRT I complex subunit VPS37A,FLJ32642,FLJ42616,HCRP1,hepatocellular carcinoma related protein 1,hVps37A,MGC116266,polyglutamine binding protein 2,PQBP2,vacuolar protein sorting 37A,Vacuolar protein sorting associated protein 37A
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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