Anti-Human/Mouse UACA Polyclonal Antibody

Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1 (By similarity).
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Properties

Data Sheet Click for Datasheet
Catalog Number PA07511
Size 100μl
Host Type Rabbit
Immunogen Fusion protein of human UACA
Specificity Highly expressed in skeletal muscle, heart, kidney and pancreas. Expressed in choroid, retina and epidermal melanocytes. Expressed in eye muscles and thyroid follicular cells.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot Q9BZF9
Concentration 0.8 mg/mL
Dilution IHC 1:30-150, ELISA 1:2000-10000
Formulation
Application IHC,ELISA
Other Names FLJ10128,KIAA1561,MGC141967,MGC141969,Nuclear membrane binding protein,NUCLING,UACA,UACA,Uveal autoantigen with coiled coil domains and ankyrin repeats,Uveal autoantigen with coiled-coil domains and ankyrin repeats
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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