Anti-Human/Mouse TRIM63 Polyclonal Antibody

This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is an E3 ubiquitin ligase that localizes to the Z-line and M-line lattices of myofibrils. This protein plays an important role in the atrophy of skeletal and cardiac muscle and is required for the degradation of myosin heavy chain proteins, myosin light chain, myosin binding protein, and for muscle-type creatine kinase.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA08668
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human TRIM63
Specificity Muscle specific. Selectively expressed in heart and skeletal muscle. Also expressed in the iris.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot Q969Q1
Concentration 0.6 mg/mL
Dilution WB 1:1000-1:5000, IHC 1:50-1:200
Formulation
Application WB,IHC,ELISA
Other Names E3 ubiquitin-protein ligase TRIM63,FLJ32380,IRF,Iris RING finger protein,MURF 1,MURF-1,MuRF1,MURF2,Muscle specific ring finger protein 1,Muscle specific ring finger protein 2,Muscle-specific RING finger protein 1,OTTHUMP00000008701,RING finger protein 28,RNF 28,RNF28,SMRZ,Striated muscle RING zinc finger protein,TRI63,TRIM 63,Trim63,Tripartite motif containing 63,tripartite motif containing 63,E3 ubiquitin protein ligase,Tripartite motif containing protein 63,Tripartite motif-containing protein 63,Ubiquitin ligase TRIM63
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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