Anti-Human/Mouse TPX2 Polyclonal Antibody

TPX2 (targeting protein for Xklp2) is a microtubule-associated protein involved in targeting the motor protein Xklp2 to microtubules. Ran-GTP activates TPX2 for the chromatin-induced microbutule assembly during M phase. Aurora-A kinase associates with TPX2 at the spindle apparatus and may regulate TPX2 via phosphorylation during the spindle assembly. TPX2 appears to play a structural role in spindle formation. TPX2 activates Eg2 in a microtubule-dependent manner by stimulating the phosphorylation and kinase activity of Eg2. 
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Properties

Data Sheet Click for Datasheet
Catalog Number PA07561
Size 100μl
Host Type Rabbit
Immunogen Fusion protein of human TPX2
Specificity Expressed in lung carcinoma cell lines but not in normal lung tissues.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot Q9ULW0
Concentration 0.9 mg/mL
Dilution WB 1:500-2000, ELISA 1:2000-5000
Formulation
Application WB,ELISA
Other Names C20ORF1,C20orf2,Chromosome 20 Open Reading Frame 1,Differentially expressed in cancerous and non-cancerous lung cells 2,Differentially expressed in cancerous and noncancerous lung cells 2,Differentially expressed in lung cells 2,Differentially expressed in lung cells,DIL 2,DIL-2,DIL2,FLS353,GD:C20orf1,HCA 519,HCA519,HCTP 4,HCTP4,Hepatocellular carcinoma associated antigen 519,Hepatocellular carcinoma-associated antigen 519,p100,Preferentially expressed in colorectal cancer,Protein fls353,REPP 86,repp86,Restricted expression proliferation associated protein 100,Restricted expression proliferation-associated protein 100,Targeting protein for Xklp2,TPX 2,TPX2,TPX2 microtubule associated homolog,TPX2 microtubule associated protein homolog,TPX2 microtubule nucleation factor,TPX2
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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