Anti-Human/Mouse TPX2 Polyclonal Antibody

Spindle assembly factor. Required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules. Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA07560
Size 100μl
Host Type Rabbit
Immunogen Fusion protein of human TPX2
Specificity Expressed in lung carcinoma cell lines but not in normal lung tissues.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot Q9ULW0
Concentration 0.7 mg/mL
Dilution WB 1:500-2000, IHC 1:30-150, ELISA 1:2000-5000
Formulation
Application WB,IHC,ELISA
Other Names C20ORF1,C20orf2,Chromosome 20 Open Reading Frame 1,Differentially expressed in cancerous and non-cancerous lung cells 2,Differentially expressed in cancerous and noncancerous lung cells 2,Differentially expressed in lung cells 2,Differentially expressed in lung cells,DIL 2,DIL-2,DIL2,FLS353,GD:C20orf1,HCA 519,HCA519,HCTP 4,HCTP4,Hepatocellular carcinoma associated antigen 519,Hepatocellular carcinoma-associated antigen 519,p100,Preferentially expressed in colorectal cancer,Protein fls353,REPP 86,repp86,Restricted expression proliferation associated protein 100,Restricted expression proliferation-associated protein 100,Targeting protein for Xklp2,TPX 2,TPX2,TPX2 microtubule associated homolog,TPX2 microtubule associated protein homolog,TPX2 microtubule nucleation factor,TPX2
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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