Anti-Human/Mouse TNN Polyclonal Antibody

This protein is involved in neurite outgrowth and cell migration in hippocampal explants.It has three EGF-like domains, one fibrinogen C-terminal domain and nine fibronectin type III domains.Tenascins are extracellular matrix proteins present during the development of organisms as well as in pathological conditions.Tenascin-W, the fourth and last member of the tenascin family remains the least well-characterized one.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA10139
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human TNN
Specificity Not detected in normal adult mammary tissues or brain but expressed in most breast tumors and brain tumors, such as glioblastomas, astrocytomas and oligodendrogliomas, tested (PubMed:17909022, PubMed:19884327). In brain tumors, detected around the endothelial cell layer of the clood vessels (PubMed:19884327).
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot Q9UQP3
Concentration 0.4 mg/mL
Dilution IHC 1:50-1:200
Formulation
Application IHC,ELISA
Other Names Tenascin-N,TENN,TN-N,TNN
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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