Anti-Human/Mouse TNFSF12 Polyclonal Antibody

Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA06076
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the Internal region of human TWEAK
Specificity Highly expressed in adult heart, pancreas, skeletal muscle, brain, colon, small intestine, lung, ovary, prostate, spleen, lymph node, appendix and peripheral blood lymphocytes. Low expression in kidney, testis, liver, placenta, thymus and bone marrow. Also detected in fetal kidney, liver, lung and brain.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot O43508
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000
Formulation
Application WB,IHC-p,IF,ELISA
Other Names APO 3 ligand,APO 3L,APO3 ligand,APO3/DR3 ligand,APO3L,DR3LG,MGC129581,MGC20669,secreted form,TNF-related weak inducer of apoptosis,TNF12,TNFSF 12,Tnfsf12,TNFSF12 protein,Tumor necrosis factor (ligand) superfamily member 12,Tumor necrosis factor ligand superfamily member 12,Tumor necrosis factor superfamily member 12,TWEAK,UNQ181/PRO207
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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