Anti-Human/Mouse TNFAIP8 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]

Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.

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Properties

Data Sheet	Click for Datasheet
Catalog Number	PA06041
Size	100μl
Host Type	Rabbit
Immunogen	Synthesized peptide derived from the Internal region of human TNF-IP 8
Specificity	Expressed at high levels in the spleen, lymph node, thymus, thyroid, bone marrow and placenta. Expressed at high levels both in various tumor tissues, unstimulated and cytokine-activated cultured cells. Expressed at low levels in the spinal cord, ovary, lung, adrenal glands, heart, brain, testis and skeletal muscle.
Isotype	IgG
Reacitivity	Human,Mouse
Clone
Uniprot	O95379
Concentration	1mg/mL
Dilution	WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:10000
Formulation
Application	WB,IHC-p,IF,ELISA
Other Names	GG2 1,Head and neck tumor and metastasis-related protein,MDC-3.13,NDED,NF-kappa-B-inducible DED-containing protein,SCC S2,SCC-S2,SCCS2,TFIP8,TNF alpha-induced protein 8,TNF induced protein,TNF-induced protein GG2-1,TNFAIP 8,TNFAIP8,Tumor necrosis factor alpha induced protein 8,Tumor necrosis factor alpha-induced protein 8
Storage	Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript	For research use only, not for use in diagnostic procedures.

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Anti-Human/Mouse TNFAIP8 Polyclonal Antibody

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