Anti-Human/Mouse SOCS7 Polyclonal Antibody

The protein as regulator signaling cascades probably through protein ubiquitination and/or sequestration. It plays an important role in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA08295
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human SOCS7
Specificity Expressed in brain and leukocytes. Also in fetal lung fibroblasts and fetal brain.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot O14512
Concentration 0.1 mg/mL
Dilution IHC 1:50-1:200
Formulation
Application IHC,ELISA
Other Names Ash and phospholipase C gamma-binding protein,NAP 4,NAP 4 Fragment,NAP-4,NAP4,Nck,Nck Ash and phospholipase C binding protein,Nck Ash and phospholipase C gamma binding protein,Nck associated protein 4,Nck-associated protein 4,NCKAP4,SH2 domain containing SOCS box protein,SOCS 7,SOCS-7,SOCS4,SOCS6,Socs7,SOCS7,Suppressor of cytokine signaling 7
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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