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Anti-Human/Mouse SLC7A5 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
Solute carrier family 7 member 5 also known as large neutral amino acids transporter small subunit 1 is a protein that in humans is encoded by the SLC7A5 gene.It is sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc.It involved in cellular amino acid uptake and the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta.Acts as an amino acid exchanger and plays a role in neuronal cell proliferation (neurogenesis) in brain.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA10800
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human SLC7A5
Specificity Expressed abundantly in adult lung, liver, brain, skeletal muscle, placenta, bone marrow, testis, resting lymphocytes and monocytes, and in fetal liver. Weaker expression in thymus, cornea, retina, peripheral leukocytes, spleen, kidney, colon and lymph node. During gestation, expression in the placenta was significantly stronger at full-term than at the mid-trimester stage. Also expressed in all human tumor cell lines tested and in the astrocytic process of primary astrocytic gliomas. Expressed in retinal endothelial cells and in the intestinal epithelial cell line Caco-2.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot Q01650
Concentration 0.5 mg/mL
Dilution WB 1:200-1:1000
Formulation
Application WB,ELISA
Other Names 4F2 LC,4F2 light chain,4F2LC,CD98,CD98 light chain,CD98LC,D16S469E,DC49,E16,hLAT1,Integral membrane protein E16,L type amino acid transporter,L type amino acid transporter 1,L-type amino acid transporter 1,Large neutral amino acids transporter 1,Large neutral amino acids transporter,Large neutral amino acids transporter small subunit 1,LAT1,LAT1,Membrane protein E16,MPE16,Slc7a5,Sodium independent neutral amino acid transporter,Sodium independent neutral amino acid transporter LAT1,Solute carrier family 7 (cationic amino acid transporter y+ system) member 5,Solute carrier family 7 member 5,TA1,Tumor associated protein 1,y+ system cationic amino acid transporter
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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