Anti-Human/Mouse SLAMF1 Polyclonal Antibody

High-affinity self-ligand important in bidirectional T-cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA03775
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the region of human SLAM.
Specificity Constitutively expressed on peripheral blood memory T-cells, T-cell clones, immature thymocytes and a proportion of B-cells, and is rapidly induced on naive T-cells after activation.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot Q13291
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-300, ELISA 1:20000
Formulation
Application WB,IHC-p,ELISA
Other Names 4933415F16,AA177906,CD 150,CD150,CD150 antigen,CDw150,Estm51,Ipo 3,IPO-3,Ipo3,MGC151472,MGC151476,OTTHUMP00000025670,OTTHUMP00000060252,RGD1560634,Signaling lymphocytic activation molecule,Signaling lymphocytic activation molecule family member 1,Signaling lymphocytic activation molecule family member 1,isoform CRA_a,Signaling lymphocytic activation molecule family member 1,isoform CRA_b,Signaling lymphocytic activation molecule precursor,Slaf1,SLAF1,SLAM family,member 1,Slamf 1,SLAMF1,SLAMF1 protein
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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