Anti-Human/Mouse SKIL Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]

The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene.

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Properties

Data Sheet	Click for Datasheet
Catalog Number	PA10567
Size	100μl
Host Type	Rabbit
Immunogen	Recombinant protein of human SKIL
Specificity	Isoform SNON and isoform SNOA are widely expressed. Highest expression is found in skeletal muscle, followed by placenta and lung. Lowest expression in heart, brain and pancreas. Isoform SNOI expression is restricted to skeletal muscle.
Isotype	IgG
Reacitivity	Human,Mouse
Clone
Uniprot	P12757
Concentration	0.4 mg/mL
Dilution	WB 1:200-1:1000, IHC 1:30-1:150
Formulation
Application	WB,IHC,ELISA
Other Names	OTTHUMP00000213557,OTTHUMP00000213591,OTTHUMP00000213592,OTTHUMP00000213595,SKI like,SKI like oncogene,Ski like protein,SKI like proto oncogene,Ski related oncogene,Ski related oncogene snoN,Ski related protein,Ski-like protein,Ski-related oncogene,Ski-related protein,SKIL,SKIL,SNO,SnoA,SnoI,SnoN
Storage	Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript	For research use only, not for use in diagnostic procedures.

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Anti-Human/Mouse SKIL Polyclonal Antibody

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