Anti-Human/Mouse SIRT4 Polyclonal Antibody

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins witHuman, Mouseono-ADP-ribosyltransferase activity. 
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Properties

Data Sheet Click for Datasheet
Catalog Number PA08165
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human SIRT4
Specificity Detected in vascular smooth muscle and striated muscle. Detected in insulin-producing beta-cells in pancreas islets of Langerhans (at protein level). Widely expressed. Weakly expressed in leukocytes and fetal thymus.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot Q9Y6E7
Concentration 0.6 mg/mL
Dilution IHC 1:25-1:100
Formulation
Application IHC,ELISA
Other Names MGC130046,MGC130047,MGC57437,NAD dependent deacetylase sirtuin 4,NAD dependent protein deacetylase sirtuin 4,NAD-dependent ADP-ribosyltransferase sirtuin-4,NAD-dependent protein deacetylase sirtuin-4,NAD-dependent protein lipoamidase sirtuin-4,mitochondrial,Regulatory protein SIR2 homolog 4,Silent mating type information regulation 2 homolog,Sir 2 like 4,SIR 2 like protein 4,Sir2 like 4,SIR2 like protein 4,SIR2-like protein 4,SIR2L 4,SIR2L4,SIR4,SIRT 4,Sirt4,Sirtuin (silent mating type information regulation 2 homolog) 4,Sirtuin (silent mating type information regulation 2 homolog) 4 (S. cerevisiae),Sirtuin 4,Sirtuin type 4,Sirtuin-4,Sirtuin4
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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