Anti-Human/Mouse SFRP1 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]

This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina.

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Properties

Data Sheet	Click for Datasheet
Catalog Number	PA10206
Size	100μl
Host Type	Rabbit
Immunogen	Synthetic peptide of human SFRP1
Specificity	Widely expressed. Absent from lung, liver and peripheral blood leukocytes. Highest levels in heart and fetal kidney. Also expressed in testis, ovary, fetal brain and lung, leiomyomal cells, myometrial cells and vascular smooth muscle cells. Expressed in foreskin fibroblasts and in keratinocytes.
Isotype	IgG
Reacitivity	Human,Mouse
Clone
Uniprot	Q8N474
Concentration	0.4 mg/mL
Dilution	IHC 1:100-1:300
Formulation
Application	IHC,ELISA
Other Names	Frizzled related protein 1,FRP 1,FRP,FRP-1,FRP1,FrzA,SARP 2,SARP-2,SARP2,Secreted apoptosis related protein 2,Secreted apoptosis-related protein 2,Secreted frizzled related protein 1,Secreted frizzled related protein,Secreted frizzled-related protein 1,SFRP 1,sFRP-1,SFRP1,SFRP1
Storage	Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript	For research use only, not for use in diagnostic procedures.

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Anti-Human/Mouse SFRP1 Polyclonal Antibody

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