Anti-Human/Mouse RXFP3 Polyclonal Antibody

Relaxin-3 is a highly conserved neuropeptide in vertebrate species and binds to the Class A G protein-coupled receptor (GPCR) RXFP3. Relaxin-3 is involved in a wide range of behaviors and targeting of RXFP3 may be relevant for a range of neurological diseases. RXFP3, confirmed that acute and chronic activation of RXFP3 increased feeding and weight gain, and produced changes in plasma leptin and insulin.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA10058
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human RXFP3
Specificity Expressed predominantly in brain regions. Highest expression in substantia nigra and pituitary, followed by hippocampus, spinal cord, amygdala, caudate nucleus and corpus callosum, quite low level in cerebellum. In peripheral tissues, relatively high levels in adrenal glands, low levels in pancreas, salivary gland, placenta, mammary gland and testis.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot Q9NSD7
Concentration 0.3 mg/mL
Dilution IHC 1:25-1:100
Formulation
Application IHC,ELISA
Other Names G protein coupled receptor GPCR135,G protein coupled receptor SALPR,G protein-coupled receptor SALPR,G-protein coupled receptor GPCR135,GPCR 135,GPCR135,Gprotein coupled receptor SALPR,Relaxin 3 receptor 1,Relaxin 3 receptor1,Relaxin 3/INSL7 receptor 1,Relaxin 3/INSL7 receptor1,Relaxin family peptide receptor 3,Relaxin family peptide receptor3,Relaxin-3 receptor 1,Relaxin/insulin like family peptide receptor 3,Relaxin3 receptor 1,Relaxin3 receptor1,RL3 R1,RL3R 1,RL3R1,RL3R1,RLN3 receptor 1,RLN3 receptor1,RLN3R1,RXFP3,RXFPR3,SALP R,SALPR,somatostatin and angiotensin like peptide receptor,Somatostatin- and angiotensin-like peptide receptor
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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