Anti-Human/Mouse/Rat XIAP Polyclonal Antibody

Apoptotic suppressor. Has E3 ubiquitin-protein ligase activity. Mediates the proteasomal degradation of target proteins, such as caspase-3, SMAC or AIFM1. Inhibitor of caspase-3, -7 and -9. Mediates activation of MAP3K7/TAK1, leading to the activation of NF-kappa-B.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA06141
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from human XIAP around the non-phosphorylation site of Ser87.
Specificity Ubiquitous, except peripheral blood leukocytes.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot P98170
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000
Formulation
Application WB,IHC-p,ELISA
Other Names AP 13,API3,Apoptosis Inhibitor 3,Baculoviral IAP repeat containing 4,Baculoviral IAP Repeat Containing Protein 4,Baculoviral IAP repeat-containing protein 4,BIRC 4,BIRC4,E3 ubiquitin-protein ligase XIAP,hIAP-3,hIAP3,HILP,IAP 3,IAP like protein,IAP-3,IAP-like protein,IAP3,ILP 1,ILP,ILP1,Inhibitor of apoptosis protein 3,Inhibitor of Apoptosis X Linked,Mammalian IAP Homologue A,MIHA,X linked IAP,X linked inhibitor of apoptosis,X linked inhibitor of apoptosis E3 ubiquitin protein ligase,X linked inhibitor of apoptosis protein,X-linked IAP,X-linked inhibitor of apoptosis protein,Xiap,XIAP,XLP2
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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