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Anti-Human/Mouse/Rat VTCN1 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
This gene encodes a protein belonging to the B7 costimulatory protein family. Proteins in this family are present on the surface of antigen-presenting cells and interact with ligand bound to receptors on the surface of T cells. Studies have shown that high levels of the encoded protein has been correlated with tumor progression. A pseudogene of this gene is located on chromosome 20. Multiple transcript variants encoding different isoforms have been found for this gene.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA10853
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human VTCN1
Specificity Overexpressed in breast, ovarian, endometrial, renal cell (RCC) and non-small-cell lung cancers (NSCLC). Expressed on activated T- and B-cells, monocytes and dendritic cells, but not expressed in most normal tissues (at protein level). Widely expressed, including in kidney, liver, lung, ovary, placenta, spleen and testis.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q7Z7D3
Concentration 0.2 mg/mL
Dilution IHC 1:25-1:100
Formulation
Application IHC,ELISA
Other Names B7 family member,H4,B7 H4,B7 homolog 4,B7 superfamily member 1,B7 superfamily,member 1,B7-H4,B7h.5,B7h4,B7S1,B7x,BC032925,Immune costimulatory protein B7-H4,Immune costimulatory protein B7H4,MGC41287,PRO1291,Protein B7S1,RP11 229A19.4,T cell costimulatory molecule B7x,T-cell costimulatory molecule B7x,V set domain-containing T cell activation inhibitor 1,V-set domain-containing T-cell activation inhibitor 1,VCTN1,Vtcn1,VTCN1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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