Anti-Human/Mouse/Rat USP16 Polyclonal Antibody

Specifically deubiquitinates histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-10' of histone H3, and is required for chromosome segregation when cells enter into mitosis. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA06098
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the Internal region of human USP16.
Specificity Present in all the tissues examined including fetal brain, lung, liver, kidney, and adult heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q9Y5T5
Concentration 1mg/mL
Dilution WB 1:500-1:2000, ELISA 1:10000
Formulation
Application WB,ELISA
Other Names Deubiquitinating enzyme 16,Human ubiquitin processing protease,MSTP039,Ubiquitin carboxyl-terminal hydrolase 16,Ubiquitin Specific peptidase 16,Ubiquitin Specific Protease 16,Ubiquitin thiolesterase 16,Ubiquitin-processing protease UBP-M,Ubiquitin-specific-processing protease 16,UBP M,UBP16,UBPM,usp16
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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