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Anti-Human/Mouse/Rat UNG Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA06092
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the Internal region of human UDG
Specificity Isoform 1 is widely expressed with the highest expression in skeletal muscle, heart and testicles. Isoform 2 has the highest expression levels in tissues containing proliferating cells.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot P13051
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000
Formulation
Application WB,IHC-p,ELISA
Other Names DGU,DKFZp781L1143,HIGM 4,HIGM4,OTTHUMP00000240527,OTTHUMP00000240528,OTTHUMP00000240529,UDG,UNG 1,UNG 15,ung,UNG,UNG1,UNG15,UNG2,Uracil DNA glycosylase 1,Uracil DNA glycosylase 2,Uracil DNA glycosylase,Uracil-DNA glycosylase
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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