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Anti-Human/Mouse/Rat TWIST2 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
The protein encoded by this gene is a basic helix-loop-helix type transcription factor and shares similarity with Twist. This protein may inhibit osteoblast maturation and maintain cells in a preosteoblast phenotype during osteoblast development. This gene may be upregulated in certain cancers. Mutations in this gene cause focal facial dermal dysplasia 3, Setleis type. Two transcript variants encoding the same protein have been found.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA07519
Size 100μl
Host Type Rabbit
Immunogen Full length of human TWIST2
Specificity In the embryo, highly expressed in chondrogenic cells. In embryonic skin, expressed in the undifferentiated mesenchymal layer beneath the epidermis which later develops into the dermis. Expressed in early myeloid cells but not in lymphoid cells in the liver. Expression also detected in the secretory ependymal epithelium of the choroid plexus primordium. In the adult, expressed in secreting glandular tissues and tubules.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q8WVJ9
Concentration 0.4 mg/mL
Dilution IHC 1:25-100, ELISA 1:2000-5000
Formulation
Application IHC,ELISA
Other Names bHLHa39,Class A basic helix-loop-helix protein 39,Dermis expressed protein 1,Dermis-expressed protein 1,DERMO 1,Dermo-1,DERMO1,MGC117334,Twist 2,Twist homolog 2 (Drosophila),Twist homolog 2,Twist related bHLH protein Dermo1,Twist related protein 2,Twist-related protein 2,Twist2,TWST2
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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