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Anti-Human/Mouse/Rat TNFSF11 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response. May also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA02448
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the C-terminal region of human RANKL.
Specificity Highest in the peripheral lymph nodes, weak in spleen, peripheral blood Leukocytes, bone marrow, heart, placenta, skeletal muscle, stomach and thyroid.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot O14788
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000-1:20000
Formulation
Application WB,IHC-p,ELISA
Other Names CD254,hRANKL2,ODF,OPGL,OPTB2,Osteoclast differentiation factor,Osteoprotegerin ligand,RANKL,Receptor activator of nuclear factor kappa B ligand,Receptor activator of nuclear factor kappa-B ligand,sOdf,TNF related activation induced cytokine,TNF-related activation-induced cytokine,TNF11,TNFSF 11,Tnfsf11,TRANCE,Tumor necrosis factor (ligand) superfamily member 11,Tumor necrosis factor ligand superfamily member 11,Tumor necrosis factor ligand superfamily member 11,soluble form
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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