Anti-Human/Mouse/Rat TAOK3 Polyclonal Antibody

The protein encoded by this gene is a serine/threonine protein kinase that activates the p38/MAPK14 stress-activated MAPK cascade but inhibits the basal activity of the MAPK8/JNK cascade. The encoded protein is a member of the GCK subfamily of STE20-like kinases.TAOK3 (TAO Kinase 3) is a Protein Coding gene. Diseases associated with TAOK3 include Kabuki Syndrome 1 and Cardiomyopathy, Familial Hypertrophic, 9. Among its related pathways are MAPK signaling pathway and p38 MAPK signaling pathway (Pathway Interaction Database). GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is TAOK1.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA04646
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the Internal region of human JIK
Specificity Ubiquitously expressed at a low level, and highly expressed in peripheral blood leukocytes (PBLs), thymus, spleen, kidney, skeletal muscle, heart and liver.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q9H2K8
Concentration 1mg/mL
Dilution WB 1:500-1:2000, ELISA 1:10000
Formulation
Application WB,ELISA
Other Names TAOK3,DPK,JIK,KDS,MAP3K18,Serine/threonine-protein kinase TAO3,Cutaneous T-cell lymphoma-associated antigen HD-CL-09,CTCL-associated antigen HD-CL-09,Dendritic cell-derived protein kinase,JNK/SAPK-inhibitory kinase,Jun kinase-inhi
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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