Anti-Human/Mouse/Rat SYK Polyclonal Antibody

SYK(spleen tyrosine kinase) is a key regulator of signal transduction events,apoptosis and orderly cell cycle progression in B-lineage lymphoid cells. Although SYK has not been linked to a human disease, defective expression of the closely related T-cell tyrosine kinase ZAP-70 has been associated with severe combined immunodeficiency(PMID:11494125). This protein has 2 isoforms produced by alternative splicing.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA05146
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from human SYK
Specificity Widely expressed in hematopoietic cells (at protein level). Within the B-cells compartment it is for instance expressed for pro-B-cells to plasma cells.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot P43405
Concentration 1mg/mL
Dilution WB 1:500-2000, ELISA 1:10000-20000
Formulation
Application WB,ELISA
Other Names EC 2.7.10.2,kinase Syk,KSYK,KSYK,p72-Syk,p72syk,Spleen tyrosine kinase,Syk,Tyrosine protein kinase SYK,Tyrosine-protein kinase SYK
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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