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Anti-Human/Mouse/Rat SULF1 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
This gene encodes an extracellular heparan sulfate endosulfatase. The encoded enzyme selectively removes 6-O-sulfate groups from heparan sulfate chains of heparan sulfate proteoglycans (HSPGs). The enzyme is secreted through the Golgi and is subsequently localized to the cell surface. The expression of this gene may be down-regulated in several types of cancer, including hepatocellular (HCC), ovarian and breast cancers. Alternative splicing results in multiple transcript variants. 
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Properties

Data Sheet Click for Datasheet
Catalog Number PA07965
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human SULF1
Specificity Expressed at highest levels in testis, stomach, skeletal muscle, lung, kidney, pancreas, small intestine and colon. It is also detected in normal ovarian surface epithelial cells. Down-regulation seen in ovarian carcinoma cell lines, ovarian cancers, breast, pancreatic, renal and hepatocellular carcinoma cell lines.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q8IWU6
Concentration 0.3 mg/mL
Dilution IHC 1:10-1:50
Formulation
Application IHC,ELISA
Other Names DSulf,Extracellular sulfatase Sulf 1,Extracellular sulfatase Sulf-1,Extracellular sulfatase Sulf1,HSULF 1,HSulf-1,Neu5,Sulf1,SULF1,Sulfatase FP,Sulfated
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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