Anti-Human/Mouse/Rat SOCS2 Polyclonal Antibody

SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS2 appears to be a negative regulator in the growth hormone/IGF1 signaling pathway. Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA05888
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the Internal region of human SOCS-2.
Specificity High expression in heart, placenta, lung, kidney and prostate.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot O14508
Concentration 1mg/mL
Dilution WB 1:500-1:2000, ELISA 1:10000
Formulation
Application WB,ELISA
Other Names CIS 2,CIS-2,CIS2,Cish 2,Cish2,Cytokine inducible SH2 protein 2,Cytokine-inducible SH2 protein 2,SOCS 2,SOCS-2,Socs2,SOCS2,SSI 2,SSI-2,SSI2,STAT induced STAT inhibitor 2,STAT-induced STAT inhibitor 2,STATI 2,STATI2,Suppressor of cytokine signaling 2
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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