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Anti-Human/Mouse/Rat SOCS1 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA08293
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human SOCS1
Specificity Expressed in all tissues with high expression in spleen, small intestine and peripheral blood leukocytes.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot O15524
Concentration 0.7 mg/mL
Dilution WB 1:1000-1:5000, IHC 1:50-1:200
Formulation
Application WB,IHC,ELISA
Other Names CISH 1,CISH1,Cytokine inducible SH2 protein 1,JAB,JAK binding protein,JAK-binding protein,Janus kinase binding protein,SOCS 1,SOCS-1,Socs1,SOCS1,SSI 1,SSI-1,SSI1,STAT induced STAT inhibitor 1,STAT-induced STAT inhibitor 1,Suppressor of cytokine signaling 1,Supressor of cytokine signalling 1,TEC interacting protein 3,Tec-interacting protein 3,TIP 3,TIP-3,TIP3
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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