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Anti-Human/Mouse/Rat SNCA Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA09737
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human SNCA
Specificity Expressed principally in brain but is also expressed in low concentrations in all tissues examined except in liver. Concentrated in presynaptic nerve terminals.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot P37840
Concentration 0.4 mg/mL
Dilution IHC 1:50-1:200
Formulation
Application IHC,ELISA
Other Names Alpha synuclein,Alpha-synuclein,Alpha-synuclein,isoform NACP140,alphaSYN,MGC105443,MGC110988,MGC127560,MGC64356,NACP,Non A beta component of AD amyloid,Non A4 component of amyloid,Non A4 component of amyloid precursor,Non-A beta component of AD amyloid,Non-A-beta component of alzheimers disease amyloid,precursor of,Non-A4 component of amyloid precursor,Non-A4 component of amyloid,precursor of,OTTHUMP00000218549,OTTHUMP00000218551,OTTHUMP00000218552,OTTHUMP00000218553,OTTHUMP00000218554,PARK 1,PARK 4,PARK1,PARK4,Parkinson disease (autosomal dominant,Lewy body) 4,Parkinson disease familial 1,SNCA,Snca synuclein,alpha (non A4 component of amyloid precursor),SYN,Synuclein alpha,Synuclein alpha 140,Synuclein,alpha (non A4 component of amyloid precursor),SYUA
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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