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Anti-Human/Mouse/Rat SMAD5 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
The protein encoded by this gene is involved in the TGF-beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. The encoded protein is activated by BMP type 1 receptor kinase. Three transcript variants encoding the same protein have been found for this gene. Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor-regulated SMAD (R-SMAD). May form trimers with the co-SMAD SMAD4. Interacts with PEBP2-alpha subunit and SMURF1. Interacts with SUV39H1 and SUV39H2. Interacts (via MH2 domain) with LEMD3. Interacts with WWP1.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA06643
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human SMAD5
Specificity Ubiquitous.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q99717
Concentration 0.2 mg/mL
Dilution WB 1:200-1:1000, IHC 1:25-1:100
Formulation
Application WB,IHC,ELISA
Other Names DKFZp781C1895,DKFZp781O1323,Dwfc,hSmad5,JV5 1,JV5-1,MAD homolog 5,MAD,mothers against decapentaplegic homolog 5,MADH 5,MADH5,Mothers against decapentaplegic homolog 5,mothers against decapentaplegic,drosophila,homolog of,5,Mothers against DPP homolog 5,MusMLP,SMA and MAD related protein 5,SMAD 5,SMAD family member 5,SMAD,mothers against DPP homolog 5,Smad5,SMAD5
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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