Anti-Human /Mouse /Rat SMAD2 Polyclonal Antibody

Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA03392
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human SMAD2 (Ab-220)
Specificity Expressed at high levels in skeletal muscle, heart and placenta.
Isotype IgG
Reacitivity Human ,Mouse ,Rat
Clone
Uniprot Q15796
Concentration 1 mg/mL
Dilution WB 1:500-1:2000, IHC 1:50-100
Formulation
Application WB,IHC
Other Names Drosophila,homolog of,MADR2,hMAD-2,HsMAD2,JV18,JV18-1,JV181,MAD,MAD homolog 2,MAD Related Protein 2,Mad-related protein 2,MADH2,MADR2,MGC22139,MGC34440,Mother against DPP homolog 2,Mothers against decapentaplegic homolog 2,Mothers against decapentaplegic,Drosophila,homolog of,2,Mothers against DPP homolog 2,OTTHUMP00000163489,Sma and Mad related protein 2,Sma- and Mad-related protein 2 MAD,SMAD 2,SMAD family member 2,SMAD,mothers against DPP homolog 2,SMAD2,SMAD2
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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