Anti-Human/Mouse/Rat SIAH1/2 Polyclonal Antibody

SIAH1 (Siah E3 Ubiquitin Protein Ligase 1) is a Protein Coding gene. Diseases associated with SIAH1 include Parkinson Disease, Late-Onset. Among its related pathways are Proteolysis Role of Parkin in the Ubiquitin-Proteasomal Pathway and Innate Immune System. GO annotations related to this gene include identical protein binding and ubiquitin-protein transferase activity. An important paralog of this gene is SIAH2. SIAH2 (Siah E3 Ubiquitin Protein Ligase 2) is a Protein Coding gene. Among its related pathways are Proteolysis Role of Parkin in the Ubiquitin-Proteasomal Pathway and Innate Immune System. GO annotations related to this gene include ligase activity and transcription corepressor activity. An important paralog of this gene is SIAH1.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA05850
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the Internal region of human Siah-1/2
Specificity SIAH1 is Widely expressed at a low level. Down-regulated in advanced hepatocellular carcinomas.SIAH2 isWidely expressed at low level.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:10000
Formulation
Application WB,IHC-p,IF,ELISA
Other Names SIAH1,HUMSIAH,E3 ubiquitin-protein ligase SIAH1,Seven in absentia homolog 1,Siah-1,Siah-1a,SIAH2,E3 ubiquitin-protein ligase SIAH2,Seven in absentia homolog 2,Siah-2,hSiah2
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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