Anti-Human/Mouse/Rat SHANK1 Polyclonal Antibody

SHANK1 seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. Plays a role in the structural and functional organization of the dendritic spine and synaptic junction.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA07318
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human SHANK1
Specificity Expressed in brain particularly in the amygdala, hippocampus, substantia nigra and thalamus. Isoform 2 seems to be expressed ubiquitously.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q9Y566
Concentration 0.3 mg/mL
Dilution WB 1:200-1000, ELISA 1:1000-2000
Formulation
Application WB,ELISA
Other Names GKAP/SAPAP interacting protein,OTTHUMP00000174437,SH3 and multiple ankyrin repeat domains 1,SH3 and multiple ankyrin repeat domains protein 1,SH3/ankyrin domain gene 1,SHAN1,SHANK 1,Shank1,Shank1a,Somatostatin receptor interacting protein,Somatostatin receptor-interacting protein,SPANK 1,SPANK1,SSTR interacting protein,SSTR-interacting protein,SSTRIP,Synamon
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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