Anti-Human/Mouse/Rat SGK1 Polyclonal Antibody

This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA10494
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human SGK1
Specificity Expressed in most tissues with highest levels in the pancreas, followed by placenta, kidney and lung. Isoform 2 is strongly expressed in brain and pancreas, weaker in heart, placenta, lung, liver and skeletal muscle.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot O00141
Concentration 0.2 mg/mL
Dilution IHC 1:25-1:100
Formulation
Application IHC,ELISA
Other Names OTTHUMP00000017247,Serine/threonine protein kinase SGK,Serine/threonine protein kinase Sgk1,Serine/threonine-protein kinase Sgk1,Serum and glucocorticoid regulated kinase,Serum/glucocorticoid regulated kinase 1,Serum/glucocorticoid regulated kinase,Serum/glucocorticoid-regulated kinase 1,SGK 1,SGK,SGK1,Sgk1 variant i3,SGK1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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