Anti-Human/Mouse/Rat SEPT8 Polyclonal Antibody

This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.SEPT8 (Septin 8) is a Protein Coding gene. Diseases associated with SEPT8 include Sexual Disorder. Among its related pathways are Bacterial invasion of epithelial cells. GO annotations related to this gene include GTP binding. An important paralog of this gene is SEPT11.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA05831
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the Internal region of human Septin 8
Specificity Widely expressed, including in brain, heart and platelets; most abundant in aorta. Isoform 2 is expressed at low levels in specific brain areas, such as occipital pole, frontal lobe, temporal lobe and putamen. Isoform 1 and 3 are highly expressed in specific brain areas, such as occipital pole, frontal lobe, temporal lobe and putamen. Isoform 2 is highly expressed in prostate, testis and ovary. Isoform 1 and isoform 3 are expressed at low levels in prostate, testis and ovary.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q92599
Concentration 1mg/mL
Dilution WB 1:500-1:2000, ELISA 1:10000
Formulation
Application WB,ELISA
Other Names KIAA0202,OTTHUMP00000211755,SEP 2,SEP2,SEPT 8,SEPT8,Septin8
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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