Anti-Human /Mouse /Rat SELENBP1 Polyclonal Antibody

This gene encodes a member of the selenium-binding protein family. Selenium is an essential nutrient that exhibits potent anticarcinogenic properties, and deficiency of selenium may cause certain neurologic diseases. The effects of selenium in preventing cancer and neurologic diseases may be mediated by selenium-binding proteins, and decreased expression of this gene may be associated with several types of cancer. The encoded protein may play a selenium-dependent role in ubiquitination/deubiquitination-mediated protein degradation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. 
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Properties

Data Sheet Click for Datasheet
Catalog Number PA03137
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human SELENBP1
Specificity Highly expressed in liver, lung, colon, prostate, kidney and pancreas. In brain, present both in neurons and glia (at protein level). Down-regulated in lung adenocarcinoma, colorectal carcinoma and ovarian cancer. Two-fold up-regulated in brain and blood from schizophrenia patients.
Isotype IgG
Reacitivity Human ,Mouse ,Rat
Clone
Uniprot Q13228
Concentration 2.62 mg/mL
Dilution WB 1:500-1:2000
Formulation
Application WB
Other Names 56 kDa selenium binding protein,56 kDa selenium-binding protein,hSBP,LPSB,SBP,SBP1,SBP1,SBP56,Selenbp1,Selenbp2,Selenium binding protein 2,Selenium binding protein1,Selenium-binding protein 1,SELNBP1,SP56
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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