Anti-Human/Mouse/Rat RYR1 Polyclonal Antibody

This gene encodes a ryanodine receptor found in skeletal muscle. The encoded protein functions as a calcium release channel in the sarcoplasmic reticulum but also serves to connect the sarcoplasmic reticulum and transverse tubule. Mutations in this gene are associated with malignant hyperthermia susceptibility, central core disease, and minicore myopathy with external ophthalmoplegia. Alternatively spliced transcripts encoding different isoforms have been described. 
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Properties

Data Sheet Click for Datasheet
Catalog Number PA08282
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human RYR1
Specificity Skeletal muscle and brain (cerebellum and hippocampus).
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot P21817
Concentration 0.3 mg/mL
Dilution WB 1:200-1:1000
Formulation
Application WB,ELISA
Other Names CCO,Central core disease of muscle,MHS,MHS1,PPP1R137,Protein phosphatase 1 regulatory subunit 137,Ryanodine receptor 1,RYDR,RYR,RYR-1,RyR1,RYR1,sarcoplasmic reticulum calcium release channel,Skeletal muscle calcium release channel,Skeletal muscle ryanodine receptor,Skeletal muscle-type ryanodine receptor,SKRR,Type 1 ryanodine receptor
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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