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Anti-Human/Mouse/Rat RUNX2 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis. Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1(I) collagen, LCK, IL-3 and GM-CSF promoters (By similarity). Inhibits MYST4-dependent transcriptional activation.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA02309
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the Internal region of human RUNX2.
Specificity Specifically expressed in osteoblasts.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q13950
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IF 1:50-1:200, ELISA 1:20000
Formulation
Application WB,IF,ELISA
Other Names Acute myeloid leukemia 3 protein,Alpha subunit 1,AML3,CBF alpha 1,CBF-alpha-1,CBFA1,CCD,CCD1,Cleidocranial dysplasia 1,Core binding factor,Core binding factor runt domain alpha subunit 1,Core binding factor subunit alpha 1,Core-binding factor subunit alpha-1,MGC120022,MGC120023,Oncogene AML 3,Oncogene AML-3,OSF 2,OSF-2,OSF2,Osteoblast specific transcription factor 2,Osteoblast-specific transcription factor 2,OTTHUMP00000016533,PEA2 alpha A,PEA2-alpha A,PEA2aA,PEBP2 alpha A,PEBP2-alpha A,PEBP2A1,PEBP2A2,PEBP2aA,PEBP2aA1,Polyomavirus enhancer binding protein 2 alpha A subunit,Polyomavirus enhancer-binding protein 2 alpha A subunit,Runt domain,Runt related transcription factor 2,Runt-related transcription factor 2,RUNX2,RUNX2,SL3 3 enhancer factor 1 alpha A subunit,SL3-3 enhancer factor 1 alpha A subunit,SL3/AKV core binding factor alpha A subunit,SL3/AKV core-binding factor alpha A subunit
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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