Anti-Human/Mouse/Rat RBM5 Polyclonal Antibody

This gene is a candidate tumor suppressor gene which encodes a nuclear RNA binding protein that is a component of the spliceosome A complex. The encoded protein plays a role in the induction of cell cycle arrest and apoptosis through pre-mRNA splicing of multiple target genes including the tumor suppressor protein p53. This gene is located within the tumor suppressor region 3p21.3, and may play a role in the inhibition of tumor transformation and progression of several malignancies including lung cancer. 
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Properties

Data Sheet Click for Datasheet
Catalog Number PA10374
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human RBM5
Specificity Isoform 5 is widely expressed in normal tissues and is expressed at increased levels in T-leukemic cell lines.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot P52756
Concentration 0.6 mg/mL
Dilution WB 1:200-1:1000, IHC 1:25-1:100
Formulation
Application WB,IHC,ELISA
Other Names FLJ39876,G15,H37,LUCA 15,LUCA15,Protein G15,Putative tumor suppressor LUCA15,RBM 5,Rbm5,RBM5,Renal carcinoma antigen NY REN 9,Renal carcinoma antigen NY-REN-9,RMB 5,RMB5,RNA binding motif protein 5,RNA binding protein 5,RNA-binding motif protein 5,RNA-binding protein 5,Tumor suppressor LUCA15
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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