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Anti-Human/Mouse/Rat RACK1 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
RACK1 (receptor for activated C kinase 1) is a 317 amino acid G protein b subunit-like protein that functions as a RACK and inhibits the activity of Src tyrosine kinases. In response to PKC activation, the intracellular localization of RACK1 and PKC bII changes, and RACK1 and PKC bII co-localize to the same sites. RACK1 is therefore thought to be a shuttling protein for PKC bII. A deficit in RACK1 may be associated with impaired PKC activation in the aging brain. 
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Properties

Data Sheet Click for Datasheet
Catalog Number PA11789
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human GNB2L1
Specificity In the liver, expressed at higher levels in activated hepatic stellate cells than in hepatocytes or Kupffer cells. Up-regulated in hepatocellular carcinomas and in the adjacent non-tumor liver tissue.1 Publication
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot P63244
Concentration 0.3 mg/mL
Dilution WB 1:500-1:2000, IHC 1:25-1:100
Formulation
Application WB,IHC,ELISA
Other Names Cell proliferation-inducing gene 21 protein,GBLP,Gnb2-rs1,Gnb2l1,Guanine nucleotide binding protein (G protein) beta polypeptide 2 like 1,Guanine nucleotide binding protein beta polypeptide 2 like 1,Guanine nucleotide binding protein beta subunit 2 like 1,Guanine nucleotide binding protein beta subunit like protein 12.3,Guanine nucleotide binding protein subunit beta 2 like 1,Guanine nucleotide binding protein subunit beta like protein 12.3,Guanine nucleotide-binding protein subunit beta-2-like 1,Guanine nucleotide-binding protein subunit beta-like protein 12.3,H12.3,HLC-7,Human lung cancer oncogene 7 protein,lung cancer oncogene 7,OTTHUMP00000223704,OTTHUMP00000223870,OTTHUMP00000223891,OTTHUMP00000223893,OTTHUMP00000223900,OTTHUMP00000223902,OTTHUMP00000223930,OTTHUMP00000223931,PIG21,Proliferation inducing gene 21,Protein homologous to chicken B complex protein guanine nucleotide binding,RACK1,Receptor for activated C kinase 1,Receptor for activated C kinase,Receptor of activated protein kinase C 1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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