Anti-Human /Mouse /Rat PTP4A3 Polyclonal Antibody

This gene encodes a member of the protein-tyrosine phosphatase family. Protein tyrosine phosphatases are cell signaling molecules that play regulatory roles in a variety of cellular processes. Studies of this class of protein tyrosine phosphatase in mice demonstrates that they are prenylated in vivo, suggesting their association with cell plasma membrane. The encoded protein may enhance cell proliferation, and overexpression of this gene has been implicated in tumor metastasis. Alternative splicing results in multiple transcript variants.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA03398
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human PTP4A3
Specificity Mainly expressed in cardiomyocytes and skeletal muscle; also found in pancreas. Consistently overexpressed in colon cancer metastasis.
Isotype IgG
Reacitivity Human ,Mouse ,Rat
Clone
Uniprot O75365
Concentration 1 mg/mL
Dilution WB 1:500-1:1000
Formulation
Application WB
Other Names Potentially prenylated protein tyrosine phosphatase,PRL 3,PRL R,PRL-3,PRL-R,PRL3,PRLR,Protein tyrosine phosphatase 4a3,Protein tyrosine phosphatase type IVA 3,Protein-tyrosine phosphatase 4a3,Protein-tyrosine phosphatase of regenerating liver 3,PTP 4A3,PTP4A3,TP4A3
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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