Anti-Human/Mouse/Rat PRKAR1B Polyclonal Antibody

Cyclic AMP-dependent protein kinase A (PKA) is an essential enzyme in the signaling pathway of the second messenger cAMP. Through phosphorylation of target proteins, PKA controls many biochemical events in the cell including regulation of metabolism, ion transport, and gene transcription. The PKA holoenzyme is composed of 2 regulatory and 2 catalytic subunits and dissociates from the regulatory subunits upon binding of cAMP.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA08812
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human PRKAR1B
Specificity Four types of regulatory chains are found: I-alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot P31321
Concentration 0.9 mg/mL
Dilution WB 1:1000-1:5000, IHC 1:50-1:200
Formulation
Application WB,IHC,ELISA
Other Names cAMP dependent protein kinase type I beta regulatory subunit,cAMP-dependent protein kinase type I-beta regulatory subunit,KAP1,PKARI beta,PRKAR 1,PRKAR 1B,PRKAR1,Prkar1b,PRKAR1B protein,Protein kinase cAMP dependent regulatory type I beta,RIbeta
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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