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Anti-Human/Mouse/Rat POU6F2 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
This gene encodes a member of the POU protein family characterized by the presence of a bipartite DNA binding domain, consisting of a POU-specific domain and a homeodomain, separated by a variable polylinker. The DNA binding domain may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner. The POU family members are transcriptional regulators, many of which are known to control cell type-specific differentiation pathways. This gene is a tumor suppressor involved in Wilms tumor (WT) predisposition. 
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Properties

Data Sheet Click for Datasheet
Catalog Number PA10739
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human POU6F2
Specificity Expressed only within the CNS, where its expression is restricted to the medical habenulla, to a dispersed population of neurons in the dorsal hypothalamus, and to subsets of ganglion and amacrine cells in the retina.1 Publication
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot P78424
Concentration 0.3 mg/mL
Dilution WB 1:200-1:1000, IHC 1:50-1:200
Formulation
Application WB,IHC,ELISA
Other Names POU class 6 homeobox 2,POU domain class 6 transcription factor 2,Retina derived POU domain factor 1,RPF 1,RPF1,Wilms tumor suppressor locus,WT 5,WT5,WTSL
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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