Anti-Human/Mouse/Rat PON1 Polyclonal Antibody

The enzyme encoded by this gene is an arylesterase that mainly hydrolyzes paroxon to produce p-nitrophenol. Paroxon is an organophosphorus anticholinesterase compound that is produced in vivo by oxidation of the insecticide parathion. Polymorphisms in this gene are a risk factor in coronary artery disease. The gene is found in a cluster of three related paraoxonase genes at 7q21.3.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA10737
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human PON1
Specificity Plasma, associated with HDL (at protein level). Expressed in liver, but not in heart, brain, placenta, lung, skeletal muscle, kidney or pancreas.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot P27169
Concentration 0.5 mg/mL
Dilution WB 1:1000-1:5000, IHC 1:50-1:200
Formulation
Application WB,IHC,ELISA
Other Names A esterase 1,A-esterase 1,Aromatic esterase 1,Arylesterase 1,Arylesterase B type,ESA,Esterase A,K 45,K-45,MVCD5,Paraoxonase 1,Paraoxonase,Paraoxonase B type,Paraoxonase,plasma,Paraoxonase1,PON 1,PON,PON1,PON1,Serum aryldiakylphosphatase,Serum aryldialkylphosphatase 1,Serum paraoxonase/arylesterase 1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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