Anti-Human/Mouse/Rat PMCH Polyclonal Antibody

PMCH (Pro-Melanin Concentrating Hormone) is a Protein Coding gene. Diseases associated with PMCH include Byssinosis. Among its related pathways are Peptide ligand-binding receptors and RET signaling. GO annotations related to this gene include melanin-concentrating hormone activity.This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include melanin-concentrating hormone (MCH), neuropeptide-glutamic acid-isoleucine (NEI), and neuropeptide-glycine-glutamic acid (NGE). Melanin-concentrating hormone is a 19-amino acid neuropeptide that stimulates hunger and may additionally regulate energy homeostasis, reproductive function, and sleep. Pseudogenes of this gene have been identified on chromosome 5.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA04942
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide from human protein
Specificity Predominantly expressed in lateral hypothalamus, also detected in pallidum, neocortex and cerebellum. Also found in thymus, brown adipose tissue, duodenum and testis (spermatogonia, early spermatocytes and Sertoli cells). No expression in peripheral blood. In brain exclusively mature MCH and NEI peptides are present. In peripheral tissues a large product, encompassing the NEI and MCH domains of the precursor, is found predominantly.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot P20382
Concentration 1mg/mL
Dilution IHC 1:50-200, ELISA 1:10000-20000
Formulation
Application IHC-p,ELISA
Other Names Melanin concentrating hormone,PMCH,Pro MCH,Pro melanin concentrating hormone
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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