Anti-Human/Mouse/Rat PIAS3 Polyclonal Antibody

Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway and the steroid hormone signaling pathway. The effects of this transcriptional coregulation, transactivation or silencing, may vary depending upon the biological context.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA05580
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the N-terminal region of human PIAS 3
Specificity Widely expressed.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q9Y6X2
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000
Formulation
Application WB,IHC-p,ELISA
Other Names E3 SUMO protein ligase PIAS 3,E3 SUMO protein ligase PIAS3,E3 SUMO-protein ligase PIAS3,FLJ14651,OTTHUMP00000015586,OTTHUMP00000015587,PIAS 3,Pias3,PIAS3 protein,PIAS3,Protein inhibitor of activated STAT 3,Protein inhibitor of activated STAT protein 3,Protein inhibitor of activated STAT3,Zinc finger MIZ type containing 5,ZMIZ 5,ZMIZ5
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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