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Anti-Human/Mouse/Rat Phospho-WNK1 (Thr60) Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
This gene encodes a member of the WNK subfamily of serine/threonine protein kinases. The encoded protein may be a key regulator of blood pressure by controlling the transport of sodium and chloride ions. Mutations in this gene have been associated with pseudohypoaldosteronism type II and hereditary sensory neuropathy type II. Alternatively spliced transcript variants encoding different isoforms have been described but the full-length nature of all of them has yet to be determined.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA01774
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from human WNK1 around the phosphorylation site of Thr60
Specificity Widely expressed, with highest levels observed in the testis, heart, kidney and skeletal muscle. Isoform 3 is kidney-specific and specifically expressed in the distal convoluted tubule (DCT) and connecting tubule (CNT) of the nephron.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q9H4A3
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:5000
Formulation
Application WB,IHC-p,ELISA
Other Names Erythrocyte 65 kDa protein,HSAN2,HSN2,hWNK1,KDP,KIAA0344,Kinase deficient protein,MGC163339,MGC163341,p65,PPP1R167,PRKWNK1,Prostate derived sterile 20 like kinase,Protein kinase lysine deficient 1,Protein kinase lysine-deficient 1,Protein kinase with no lysine 1,Protein phosphatase 1,regulatory subunit 167,PSK,Serine/threonine protein kinase WNK1 1,Serine/threonine protein kinase WNK1 2,Serine/threonine protein kinase WNK1,Serine/threonine-protein kinase WNK1,With no K,WNK lysine deficient protein kinase 1,WNK lysine deficient protein kinase 1 isoform,WNK1,WNK1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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