Anti-Human/Mouse/Rat Phospho-TPH1 (Ser58) Polyclonal Antibody

This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA01818
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from human TPH1 around the phosphorylation site of S58.
Specificity Isoform 2 seems to be less widely expressed than isoform 1.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot P17752
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000
Formulation
Application WB,IHC-p,ELISA
Other Names Indoleacetic acid 5 hydroxylase,L tryptophan hydroxylase,MGC119994,TPH 1,TPH,TPH1,TPH1,TPRH,TRPH,Tryptophan 5 hydroxylase 1,Tryptophan 5 monooxygenase 1,Tryptophan 5 monooxygenase,Tryptophan 5-hydroxylase 1,Tryptophan 5-monooxygenase 1,Tryptophan hydroxylase 1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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