Anti-Human/Mouse/Rat Phospho-SYK (Tyr348) Polyclonal Antibody

SYK(spleen tyrosine kinase) is a key regulator of signal transduction events,apoptosis and orderly cell cycle progression in B-lineage lymphoid cells. Although SYK has not been linked to a human disease, defective expression of the closely related T-cell tyrosine kinase ZAP-70 has been associated with severe combined immunodeficiency(PMID:11494125). This protein has 2 isoforms produced by alternative splicing.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA05124
Size 100μl
Host Type Rabbit
Immunogen Synthesized phospho derived from human SYK (Phospho-Tyr348)
Specificity Widely expressed in hematopoietic cells (at protein level). Within the B-cells compartment it is for instance expressed for pro-B-cells to plasma cells.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot P43405
Concentration 1mg/mL
Dilution WB 1:500-2000, ELISA 1:10000-20000
Formulation
Application WB,ELISA
Other Names EC 2.7.10.2,kinase Syk,KSYK,KSYK,p72-Syk,p72syk,Spleen tyrosine kinase,Syk,Tyrosine protein kinase SYK,Tyrosine-protein kinase SYK
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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