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Anti-Human/Mouse/Rat Phospho-PDCD4 (Ser457) Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
This gene is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding. Alternative splicing results in multiple transcript variants.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA01822
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from human Pdcd-4 around the phosphorylation site of S457.
Specificity Up-regulated in proliferative cells. Highly expressed in epithelial cells of the mammary gland. Reduced expression in lung cancer and colon carcinoma.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q53EL6
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000
Formulation
Application WB,IHC-p,ELISA
Other Names Death up-regulated gene protein,Dug,H731,Ma3,MGC33046,MGC33047,Neoplastic transformation inhibitor,Neoplastic transformation inhibitor protein,Nuclear antigen H731,Nuclear antigen H731 like,Nuclear antigen H731 like protein,Nuclear antigen H731-like,PDCD 4,Pdcd4,PDCD4,Programmed cell death 4,programmed cell death 4 (neoplastic transformation inhibitor),Programmed cell death protein 4,Protein 197/15a,Protein MA-3,Tis,Topoisomerase-inhibitor suppressed protein
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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