Anti-Human/Mouse/Rat Phospho-MAP3K7 (Thr187) Polyclonal Antibody

Component of a protein kinase signal transduction cascade. Mediator of TRAF6 and TGF-beta signal transduction. Activates IKBKB and MAPK8 in response to TRAF6 signaling. Stimulates NF-kappa-B activation and the p38 MAPK pathway. In osmotic stress signaling, plays a major role in the activation of MAPK8/JNK, but not that of NF-kappa-B.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA01700
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from human Tak1 around the phosphorylation site of Thr187
Specificity Isoform 1A is the most abundant in ovary, skeletal muscle, spleen and blood mononuclear cells. Isoform 1B is highly expressed in brain, kidney and small intestine. Isoform 1C is the major form in prostate. Isoform 1D is the less abundant form.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot O43318
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000
Formulation
Application WB,IHC-p,ELISA
Other Names M3K7,MAP3K 7,Map3k7,MEKK7,Mitogen activated protein kinase kinase kinase 7,Mitogen-activated protein kinase kinase kinase 7,TAK1,TGF beta activated kinase 1,TGF-beta-activated kinase 1,TGF1a,Transforming growth factor beta activated kinase 1,Transforming growth factor-beta-activated kinase 1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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